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Morphine-6-glucuronide: Actions and Mechanisms

โœ Scribed by Gavin J. Kilpatrick; Terry W. Smith


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Morphine-6-glucuronide: Actions and mech
โœ Gavin J. Kilpatrick; Terry W. Smith ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 380 KB

## Abstract Morphineโ€6โ€glucuronide (M6G) appears to show equivalent analgesia to morphine but to have a superior sideโ€effect profile in terms of reduced liability to induce nausea and vomiting and respiratory depression. The purpose of this review is to examine the evidence behind this statement an

A synthesis of morphine-6-glucuronide
โœ Christopher Lacy; Malcolm Sainsbury ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 106 KB
Synthesis of morphine 6-ฮฑ-d-glucuronide
โœ Igor Rukhman; Arie L Gutman ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 108 KB

This paper provides the ยฎrst report on stereoselective synthesis and characterization of morphine 6-a-dglucuronide (M6aG), useful as a reference marker for testing the purity and stability of the pharmaceutically important morphine 6-b-d-glucuronide (M6G). The synthesis is based on the glycosylation