Montmorillonite K-10 Mediated Erlenmeyer Synthesis of 4-Arylmethylene-2-phenyl-5(4H)-oxazolones.
โ Scribed by N. N. Karade; S. G. Shirodkar; B. M. Dhoot; P. B. Waghmare
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 17 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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Reaction of 4-arylidene-2-phenyl-5(4H)-1,3-oxazolones with benzyne afforded predominantly, 3-arylidene-7-hydroxy-7phenyl-1,4(H)-benzoxazepine-2-ones in addition to their N-phenyl derivatives. However, the reaction of the target oxazolones with an excess of benzyne gave only the N-phenyl derivatives
## Abstract Methyl 2โbenzoylaminoโ3โoxobutanoate (3) was prepared from hippuric acid (1) which was converted with __N,Nโ__dimethylacetamide and phosphorus oxychloride into 4โ(1โdimethylaminoethylidene)โ2โphenylโ5(4__H__)โoxazolone (2) followed by hydrolysis with hydrochloric acid in methanol. Compo