Denaturation of model proteinlike molecules at the liquid-solid interface is simulated over a wide temperature range by employing the lattice Monte Carlo technique. Initially, the molecule containing 27 monomers of two types (A and B) is assumed to be adsorbed in the native folded state (a 3 ุ 3 ุ 3
Monte Carlo simulation of diffusion of adsorbed proteins
โ Scribed by V.P. Zhdanov; B. Kasemo
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 164 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0887-3585
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โฆ Synopsis
We present the results of threedimensional lattice Monte Carlo simulations of protein diffusion on the liquid-solid interface in a wide temperature range including the most interesting temperatures (from slightly below T f and up to T c , where T f and T c are the folding and collapse temperatures). For the model under consideration (27 monomers of two types), the temperature dependence of the diffusion coefficient is found to obey the Arrhenius law with the normal value (ฯท10 ุ2 ุ 10 ุ3 cm 2 /s) of the preexponential factor. Proteins 2000;39:76 -81.
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