Monozygotic twins concordant for intestinal Behçet’s disease
✍ Scribed by Taku Kobayashi; Yuichiro Sudo; Shozo Okamura; Shinji Ohashi; Fumihiro Urano; Tsutomu Hosoi; Kose Segawa; Nobuhisa Mizuki; Masao Ota
- Publisher
- Springer Japan
- Year
- 2005
- Tongue
- English
- Weight
- 244 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0944-1174
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Deletions within chromosome band 22q11.2 are associated with a variety of conditions, although a simple genotype-phenotype correlation has not been established so far. Environmental factors, chance events, or a second hit theory were supported by two observations of monozygotic twins with 22q11.2 de
We have observed two female identical twins with Crouzon syndrome with an FGFR2 mutation. The twins were born to a 25-year-old Japanese mother and a 31-year-old father. No other member of the family had Crouzon syndrome. Monozygosity and concordance for Crouzon syndrome were established by DNA seque
al 1 recently published their experience with infliximab for induction and maintenance of remission in 6 patients with intestinal Behc ¸et's disease (BD). Other reports have also shown the efficacy of infliximab in inducing remission in intestinal BD. [2][3][4][5][6][7] However, many of these patien