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Monomeric IgE Stimulates Signaling Pathways in Mast Cells that Lead to Cytokine Production and Cell Survival

✍ Scribed by Janet Kalesnikoff; Michael Huber; Vivian Lam; Jacqueline E Damen; Juan Zhang; Reuben P Siraganian; Gerald Krystal


Book ID
117723072
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
417 KB
Volume
14
Category
Article
ISSN
1074-7613

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We recently reported that extracellular ATP was mitogenic for Swiss 3T3, 3T6, and A431 cells (Huang et al.: Proc. Natl. Acad. Sci. USA, 86:7904-7908, 1989). Here we examined the possible involvement of activation of the protein kinase C (PKC) signal transduction pathway in the mechanism of action o