Hepatic warm ischemia and reperfusion (IR) injury occurs in many clinical situations and has an important link to subsequent hepatic failure. The pathogenesis of this injury involves numerous pathways, including mitochondrial-associated apoptosis. We studied the effect of mitochondrial calcium uptak
Monoethylglycinexylidide Formation as an Independent Measure of Warm Hepatic Ischemia and Reperfusion Injury
β Scribed by R.Matthew Walsh; Jun-ichi Tanaka; Paul S. Malchesky; Naoki Sato; Shin-ichi Nakayama; David P. Vogt; Thomas A. Broughan; Robert E. Hermann; William J. Castellani
- Book ID
- 115634854
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 325 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0022-4804
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π SIMILAR VOLUMES
ism itself. A number of hypotheses have been articulated to Advances in liver surgery and transplantation have provide mechanistic explanations for reperfusion injury: free lead to a steady increase in the number of these interradical generation and attack of unsaturated lipids, proteins, ventions.
Hepatic ischemia and reperfusion causes neutrophildependent liver injury. Although the mechanisms of ischemia/reperfusion-induced liver neutrophil recruitment are somewhat understood, less is known regarding the early events that initiate the inflammatory injury. Using a murine model of partial hepa