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Monocytes and CD4+ T cells contribution to the under-expression of NR4A2 and TNFAIP3 genes in patients with multiple sclerosis

✍ Scribed by Navone, N.D.; Perga, S.; Martire, S.; Berchialla, P.; Malucchi, S.; Bertolotto, A.


Book ID
122211656
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
318 KB
Volume
272
Category
Article
ISSN
0165-5728

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✍ Koen Venken; Niels Hellings; Karen Hensen; Jean-Luc Rummens; Robert Medaer; Mari πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 645 KB

## Abstract Accumulating evidence indicates an immunosuppressive role for CD4^+^CD25^+^ regulatory T cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with relapsing‐remitting multiple sclerosis (RR‐MS) has been reported recently, no information is available so fa