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Monoclonal Antibody to Blood Group Glycosyltransferases, Produced by Hybrids Constructed with Epstein-Barr-Virus-Transformed B Lymphocytes from a Patient with ABO-Incompatible Bone Marrow Transplant and Mouse Myeloma Cells

✍ Scribed by Yoshihiko Kominato; Takashi Fujikura; Ichirou Shimada; Hisao Takizawa; Kyoko Hayashi; Takao Mori; Tamotsu Matsuda

Book ID: 115109634
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 333 KB
Volume: 59
Category: Article
ISSN: 0042-9007
DOI: 10.1111/j.1423-0410.1990.tb05022.x

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A method of producing human monoclonal antibody by combining somatic cell hybridization technology with the capability of Epstein-Barr virus (EBV) to transform human B lymphocytes is described. Peripheral blood lymphocytes from a donor with positive tuberculin skin test reaction were transformed by