## Abstract We evaluated the potential for polyelectrolyte induced precipitation of antibodies to replace traditional chromatography purification. We investigated the impact of solution pH, solution ionic strength and polyelectrolyte molecular weight on the degree of precipitation using the anionic
โฆ LIBER โฆ
Monoclonal antibody purification using cationic polyelectrolytes: An alternative to column chromatography
โ Scribed by Thanmaya Peram; Paul McDonald; Jayme Carter-Franklin; Robert Fahrner
- Publisher
- American Institute of Chemical Engineers
- Year
- 2010
- Tongue
- English
- Weight
- 381 KB
- Volume
- 26
- Category
- Article
- ISSN
- 8756-7938
- DOI
- 10.1002/btpr.437
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Selective antibody precipitation using p
โ
Paul McDonald; Corazon Victa; Jayme N. Carter-Franklin; Robert Fahrner
๐
Article
๐
2009
๐
John Wiley and Sons
๐
English
โ 160 KB
๐ 2 views
Reactivation of glyceraldehyde-3-phospha
โ
M. B. Dainiak; V. A. Izumrudov; V. I. Muronetz; I. Yu. Galaev; B. Mattiasson
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 91 KB
๐ 1 views
The simplified model of chaperone action when the inactive misfolded forms are removed from the reaction media preventing aggregation was developed using antibodies in combination with polyelectrolyte complexes. The antibodies, which bind specifically inactive dimers of glyceraldehyde-3-phosphate de