Monoclonal antibody-defined T-cell phenotypes and phytohemagglutinin reactivity of E-rosette-forming circulating lymphocytes from untreated chronic myelocytic leukemia patients

✍ Scribed by Andrea Velardi; Pietro Rambotti; Cristina Cernetti; Fabrizio Spinozzi; Roberto Gerli; Massimo F. Martelli; Stephen Davis

• Publisher: John Wiley and Sons
• Year: 1984
• Tongue: English
• Weight: 395 KB
• Volume: 53
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19840215)53:4<913::aid-cncr2820530416>3.0.co;2-m

✦ Synopsis

T-cell phenotypes, as defined by murine monoclonal antibodies, (OKT3, OKT4, OKT8, OKIal), and phytohemagglutinin (PHA) reactivity, were evaluated in E-rosette forming cells (T-cells) from 10 untreated chronic myelocytic leukemia patients. The proportion of T4+ cells was lower in patients than in controls