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Monoclonal antibodies to human kidney gamma-glutamyltransferase

✍ Scribed by Raphael Donati; Nicole Sabolovic; Maria Wellman; Yves Artur; Gérard Siest


Book ID
115826336
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
893 KB
Volume
174
Category
Article
ISSN
0009-8981

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Eighteen IgG1 monoclonal antibodies (Mabs) have been produced against gamma-glutamyl transferase (GGT) from rat kidney. They were specific to the light subunit of the enzyme with affinity constants ranging from 0.3 to 7.5 10(8) M-1, while they did not react with GGT from other sources i.e. human and