Monoclonal antibodies to human heart fatty acid-binding protein
β Scribed by W. Roos; E. Eymann; M. Symannek; J. Duppenthaler; K.W.H. Wodzig; M. Pelsers; J.F.C. Glatz
- Book ID
- 113181702
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 418 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0022-1759
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In order to develop specific antibodies against human heart cytoplasmic fatty acid-binding protein (H-FABPc), four oligo-peptides of 15-20 amino-acids each and corresponding with different antigenic parts of the human H-FABPc molecule, were synthesized. Polyclonal antibodies against these synthetic
l-leart contains a fatty acid binding protein (I:ABP) concentration comparable to liver, when it is determined with a fatty acid-binding assay. The low concentration detected with anti-liver FABP antibodies is related to the different chemical forms and physiochemical properties of liver and heart F