Type II DNA topoisomerases are enzymes capable of transporting one DNA duplex through another by performing a cycle of DNA cleavage, transport, and religation, coupled to ATP binding and hydrolysis. Here, we considered a coarse-grained model of the structure and investigated the motions within two s
โฆ LIBER โฆ
Monoclonal antibodies to human DNA topoisomerase I and to the two isoforms of DNA topoisomerase II: 170 and 180 Kd isozymes
โ Scribed by Giulia C.B. Astaldi Ricotti; Claudia Negri; Cinzia Sala; Roberto Chiesa
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 76 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0192-0561
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The possible involvement of DNA topoisomerase I in cell transition from C , to G , and in progression through the cell cycle was studied by estimating the ability of human peripheral blood lymphocytes to undergo mitogenic stimulation in the presence of the topoisomerase I inhibitor camptothecin (CAM