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Monoclonal antibodies to ethanol induced cytochrome P-450 that inhibit aniline and nitrosamine metabolism

✍ Scribed by Sang S. Park; In-Young Ko; Christopher Patten; Chung S. Yang; Harry V. Gelboin


Book ID
115779097
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
328 KB
Volume
35
Category
Article
ISSN
0006-2952

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The monoclonal antibody MAb 1-68-11, prepared to constitutive cytochrome P450 IIC11 (2c/RLM5) from male Sprague-Dawley rat liver, was used to study the contribution of the class of cytochrome P450s epitopically related to P450 IIC11 to the regiospecific metabolism of benzo[a]pyrene (BP) and its bind