Monoclonal antibodies in detection of choroidal melanoma
β Scribed by P. J. Ringens; R. Haperen; C. Vennegoor; P. T. V. M. Jong; S. G. Duinen; D. J. Ruiter; A. W. M. Kamp
- Book ID
- 112710175
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 890 KB
- Volume
- 227
- Category
- Article
- ISSN
- 0065-6100
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Several laboratories have now shown that monoclonal antibodies having enzyme-like properties can be generated. The generation of catalytic antibodies makes use of the same basic procedures that have been used for the generation of binding monoclonal antibodies, yet the process involves an additional
## Abstract Monoclonal antibodies (MAbs) directed against __Xiphophorus__ melanoma cells were developed and tested by indirect immunofluorescence and immunoperoxidase staining for reactivity with a panel of 15 allogeneic tissues and 12 allogeneic cell lines. The reactivity of such MAbs was restrict