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Monoclonal antibodies (IgM) against a murine carcinoma, Lewis lung carcinoma Lewis lung carcinoma (3LL): production, purification and in vitro selectivity

✍ Scribed by Patrick Midoux; Annie-Claude Roche; Michel Monsigny


Book ID
104176634
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
399 KB
Volume
8
Category
Article
ISSN
0165-2478

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## Abstract Lewis lung carcinoma (3LL) is a spontaneous murine lung carcinoma which preferentially metastasizes into the lung. Monoclonal antibodies (MAb) against 3LL cells were prepared by fusing spleen cells from rats immunized with 3LL and the P3‐NSI/I‐Ag4 (NSI) plasmacytoma. Two hybridomas were