Monoclonal antibodies help in the differential diagnosis of “small round cell” childhood tumours
- Book ID
- 122801819
- Publisher
- Elsevier Science
- Year
- 1982
- Weight
- 187 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0277-5379
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The monoclonal antibody (MAb), FMG25, raised following immunization of mice with the human T cell line HUT 78, binds to human neuroblastoma but not to other small roundcell tumours of childhood (rhabdomyosarcoma and Ewing's sarcoma). The specificity of the reagent is paralleled on normal tissues bin
## Abstract Small round cell tumors are among the most common problems in the differential diagnosis of cancer, even when more sophisticated histological techniques are utilized (Ezinger and Weiss: In __Soft Tissue Tumors__. St. Louis: CV Mosby, 1988, pp 668–683). Six cases of small round cell tumo
of new laboratory based, medically essential tests. Direction, thus, is analyzing, concluding and deciding on a course or direction while at the same time brokering the appropriation of new tests into the laboratory, transferring simple tests to others and ensuring managers and management perform to