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Monoclonal antibodies from mice bearing polyoma virus-induced tumor

✍ Scribed by Neomi Moav; Nechama I. Smorodinsky; Ben-Ami Balin; Isaac P. Witz


Book ID
104660433
Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
724 KB
Volume
12
Category
Article
ISSN
0340-7004

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A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP