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Monoclonal antibodies capable of discriminating the human inhibitory Fcγ-receptor IIB (CD32B) from the activating Fcγ-receptor IIA (CD32A): biochemical, biological and functional characterization

✍ Scribed by Maria-Concetta Veri; Sergey Gorlatov; Hua Li; Steve Burke; Syd Johnson; Jeffrey Stavenhagen; Kathryn E. Stein; Ezio Bonvini; Scott Koenig


Book ID
108782085
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
1006 KB
Volume
121
Category
Article
ISSN
0019-2805

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## Abstract ## Objective Fcγ receptors (FcγRs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcγRIIb in rheumatoid arthritis (RA) by studying the effect o