𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Monoclonal antibodies: boundless potential, daunting challenges

✍ Scribed by Theodore J. Torphy

Book ID
104361697
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
34 KB
Volume
13
Category
Article
ISSN
0958-1669

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## Abstract We and others have reported that multiple autoantibodies are unmasked in human polyclonal antibody preparations after exposure to physiological oxidizing agents (hemin) or electromotive force. We now have asked if oxidation unmasks autoantibody reactivities in monoclonal antibodies (mAb