Monoclonal antibodies against squamous cell carcinoma of the upper aerodigestive mucous membranes
β Scribed by Tibor Goeroegh; Benedikt J. Folz; Jochen A. Werner
- Book ID
- 117402860
- Publisher
- SAGE Publications
- Year
- 1997
- Tongue
- English
- Weight
- 112 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0194-5998
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## Abstract In an attempt to define the true frequency of multiple primary squamouscell carcinomas of the upper aerodigestive tract, 3 separate population groups were studied. The results of this investigation confirmed the high incidence of multicentric carcinomas in the upper aerodigestive tract,
## Abstract ## Background. The trifunctional bispecific antibody Removab (tbAB) bridges and activates CD3 positive T cells to EpCAM on carcinoma cells and simultaneously binds to an accessory immuneβcell inducing tumor cell lysis. tbABβinduced tumor cytotoxicity was assessed in an autologous human