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Monoclonal and anti-idiotypic antibodies and the elucidation of receptor structure

✍ Scribed by J. Craig Venter

Book ID
112936739
Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
336 KB
Volume
2
Category
Article
ISSN
0257-277X

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Disialoganglioside GD2 anti-idiotypic mo
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Disialoganglioside GD2 is widely expressed among neuroblastomas, melanomas, small-cell lung carcinoma, sarcomas and brain tumors. Immunity directed against this antigen may have anti-tumor utility. Since GDz is poorly immunogenic, antiidiotypic antibodies may serve as alternative tumor vaccines. Mon