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Monoamine oxidase activity reduced in cultured human fetal cells deficient in hypoxanthine-guanine phosphoribosyltransferase activity

✍ Scribed by S. D. Skaper; I. A. Schafer

Publisher
Springer
Year
1978
Tongue
English
Weight
164 KB
Volume
16
Category
Article
ISSN
0006-2928

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## Abstract Nine independently derived clones of mutagenized rat hepatoma cells selected for resistance to 6‐mercaptopurine (6‐MP) or 6‐thioguanine (6‐ThioG) have been isolated. Each has severely reduced catalytic activity of hypoxanthine‐guanine phosphoribosyltransferase (HPRT) and seven of them p