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Mono-Unsaturated Metabolites of Valproic Acid in Epileptic Women and Their Neonates

โœ Scribed by Tsuyoshi Kondo; Koichi Otani; Takayuki Hirano; Sunao Kaneko; Yutaka Fukushima; Tokijiro Sato; Yukimitsu Nomura; Yoshihiro Ogawa


Book ID
118708208
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
201 KB
Volume
41
Category
Article
ISSN
1323-1316

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Pharmacokinetics of valproic acid and me
โœ Heinz Nau; Rainer Zierer ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 603 KB

## Abstract Human therapeutic valproic acid (VPA) levels could be maintained in the mouse for a period of 1 week by constant rate application via subcutaneously implanted osmotic minipumps. Also, the concentrations of VPA metabolites observed in mouse plasma were similar to those seen in human plas