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Monitoring time-dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry

✍ Scribed by Patterson, Nathan Heath; Thomas, Aurélien; Chaurand, Pierre


Book ID
126828448
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
617 KB
Volume
49
Category
Article
ISSN
1076-5174

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## Abstract A qualitative and quantitative analysis of erlotinib (RO0508231) and its metabolites was carried out on rat tissue sections from liver, spleen and muscle. Following oral administration at a dose of 5 mg/kg, samples were analyzed by matrix‐assisted laser desorption ionization (MALDI) wit