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Monitoring of engraftment and progression of acute lymphoblastic leukemia in individual NOD/SCID mice

✍ Scribed by Bart A Nijmeijer; Paul Mollevanger; Shama L van Zelderen-Bhola; Hanneke C Kluin-Nelemans; Roel Willemze; J.H.Frederik Falkenburg


Book ID
114216593
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
186 KB
Volume
29
Category
Article
ISSN
0301-472X

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Engraftment of chronic myeloid leukemia
✍ Christine F. Hoyle; Robert S. Negrin πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 290 KB πŸ‘ 2 views

Chronic myeloid leukemia (CML) is a clonal disorder of primitive hematopoietic stem cells characterized by a reciprocal translocation between chromosomes 9 and 22. Animal models of CML would be useful to study the biology and potential therapies in this disease. Mice with severe combined immunodefic