Monitoring of cyclosporin in whole blood by reversed-phase liquid chromatography on a butyl column
β Scribed by W.E. Lambert; A.P. De Leenheer; H.R. Walgraeve; W. Tassaneeyakul
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 244 KB
- Volume
- 427
- Category
- Article
- ISSN
- 0378-4347
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A sensitive high-performance liquid chromatographic (HPLC) method for a ' prodrug of tranexamic acid (KABI 2161) in whole blood is described. Since KABI 2161 is rapidly hydrolysed in whole blood the samples are collected directly into the extraction tubes and extracted immediately. After pre-column
## Abstract Therapy with cyclosporin A (CsA) for immunosuppression after organ transplantation requires monitoring of its levels in blood owing to the narrow therapeutic index of the drug and to the high interβindividual variability of the drug absorption and metabolism. We describe the preparation