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Monitoring of ajmaline in plasma with high-performance liquid chromatography

✍ Scribed by Claus Köppel; Angelika Wagemann; Günter Roland Hansen; Christian Müller

Publisher
Elsevier Science
Year
1992
Weight
437 KB
Volume
575
Category
Article
ISSN
0378-4347

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High-performance liquid chromatography of deacetylmetipranolol in plasma
✍ M. Tkaczykovát; L. Šafařík 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 336 KB

A sensitive high-performance liquid chromatographic method with electro-chemical detection is developed for the determination of deacetylmetipranolol (DMP), an active metabolite of beta-sympatholytic drug metipranolol (MP). DMP is extracted from the plasma after basifying with dichloromethane. After