Monitoring of acute myeloid leukemia by flow cytometry
β Scribed by Wolfgang Kern; Susanne Schnittger
- Book ID
- 107546214
- Publisher
- Current Science Inc.
- Year
- 2003
- Tongue
- English
- Weight
- 616 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1523-3790
No coin nor oath required. For personal study only.
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The value of flow cytometric detection of myeloperoxidase (MPO) in the differential diagnosis of acute leukemia was evaluated in 57 cases of acute leukemia and in 9 leukemia cell lines. Cells were fixed and permeabilized with Fix & Perm cell permeabilization kit at room temperature for 15 min each,
## Abstract Two highly sensitive methods, multiparameter flow cytometry (MFC) and realβtime quantitative PCR (RQβPCR), are increasingly used to monitor minimal residual disease (MRD) and to guide riskβadapted management in acute myeloid leukemia (AML). An independent prognostic impact has been demo