Monitoring Human Exposure to Carcinogenic and Mutagenic Agentsby A. Berlin; M. Draper; K. Hemminki; H. Vainio

K-ras mutations in human adenocarcinoma

K-ras mutations in human adenocarcinoma of the lung: Association with smoking and occupational exposure to asbestos

✍ K. Husgafvel-Pursiainen; P. Hackman; M. Ridanpää; S. Anttila; A. Karjalainen; T. 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 784 KB

## Abstract We investigated point mutational activation of the __ras__ genes (K‐__ras__ codons 12, 13 and 61; N‐__ras__ codons 12, 13 and 61; H‐__ras__ codons 12 and 61) in primary, resected lung cancer by dot blotting and oligonucleotide hybridization. K‐__ras__ mutations were found in 14 (29%) of