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Monitoring for new multiple congenital anomalies in the search for human teratogens

✍ Scribed by Khoury, Muin J. ;Botto, Lorenzo ;Waters, Grady D. ;Mastroiacovo, Pierpaolo ;Castilla, Eduardo ;Erickson, J. David


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
667 KB
Volume
46
Category
Article
ISSN
0148-7299

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von Willebrand Disease (vWD) is the most frequently inherited bleeding disorder in humans, and is caused by a qualitative and/or quantitative abnormality of the von Willebrand factor (vWF). A large number of defects that cause qualitative variants have been located in the A1 domain of the vWF, which