Monitoring disease progression using high-density motor unit number estimation in amyotrophic lateral sclerosis
β Scribed by Johannes P. van Dijk; Helenius J. Schelhaas; Ivo N. Van Schaik; Henny M.H.A. Janssen; Dick F. Stegeman; Machiel J. Zwarts
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 426 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Limitations associated with global measures of function in patients with amyotrophic lateral sclerosis (ALS) and the qualitative nature of needle electromyography have stimulated the development of alternate means of monitoring disease severity and progression in ALS. Thus, the objectiv
In some patients with amyotrophic lateral sclerosis (ALS), the thenar hand is more severely affected than the hypothenar hand. To quantify the dissociated involvement, we examined the motor unit number estimate (MUNE) of both the abductor pollicis brevis (APB) and abductor digiti minimi (ADM) muscle
The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasion