Closed system generation of dendritic ce
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M. Elias; J. van Zanten; G.A.P. Hospers; A. Setroikromo; M.A. de Jong; L.F.M.H.
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Article
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2005
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John Wiley and Sons
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English
⚖ 440 KB
Dendritic cells (DC) used for clinical trials should be processed on a large scale conforming to current good manufacturing practice (cGMP) guidelines. The aim of this study was to develop a protocol for clinical grade generation of immature DC in a closed-system. Aphereses were performed with the C