Targeting PKC-mediated signal transducti
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Peter P. Ruvolo; Liran Zhou; Julie C. Watt; Vivian R. Ruvolo; Jared K. Burks; Ti
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Article
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2011
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John Wiley and Sons
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English
โ 569 KB
Recent studies in acute myeloid leukemia (AML) suggest activation of pro-proliferative signaling cascades including those mediated by protein kinase C (PKC) represent a poor prognostic factor for patients. The classical PKC isoforms a and b generally support survival signaling and have emerged as im