Molecular studies of the fragile X syndrome
β Scribed by Knight, Samantha J. L. ;Hirst, Mark C. ;Roche, Anya ;Christodoulou, Zoe ;Huson, Susan M. ;Winter, Robin ;Fitchett, Margaret ;McKinley, Mark J. ;Lindenbaum, Richard H. ;Nakahori, Yutaka ;Davies, Kay E.
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 522 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0148-7299
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We report on a series of 453 mentally retarded subjects investigated for fragile X syndrome from 1982 to July 1995. The 22% rate of efficiency of FRAX positivity indicated a significant preselection by the c h icians. However, this rate dropped to ll% in the last year. Since 1992, Southern blot anal
## Abstract Since the identification of the FMR1 gene basic research has been focused on the molecular characterization of the FMR1 gene product, the fragile X mental retardation protein (FMRP). Recent developments in fragile X research have provided new insights and knowledge about the physiologic
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