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Molecular structure of the IL-3, GM-CSF and IL-5 receptors

✍ Scribed by Atsushi Miyajima


Book ID
112212341
Publisher
AlphaMed Press
Year
1992
Tongue
English
Weight
865 KB
Volume
10
Category
Article
ISSN
1066-5099

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The AML14.3D10 human myeloid leukemic cell line expresses receptors for granulocytemacrophage colony stimulating factor (GM-CSF) and interleukin-5 (IL-5), but not IL-3. We have found that this cell line produces GM-CSF in amounts up to 113 pg/ml in culture supernatants. Deprivation of endogenous GM-