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Molecular simulation reveals structural determinants of the hanatoxin binding in Kv2.1 channels

✍ Scribed by Yu-Shuan Shiau; Tze-Bin Lin; Horng-Huey Liou; Po-Tsarng Huang; Kuo-Long Lou; Yuh-Yuan Shiau


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
221 KB
Volume
8
Category
Article
ISSN
1610-2940

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Molecular determinants of the hanatoxin
✍ Kuo-Long Lou; Po-Tsang Huang; Yu-Shuan Shiau; Yuh-Yuan Shiau πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

## Abstract The carboxyl terminus of S3 segment (S3~C~) in voltage‐gated potassium channels was proposed to bear the binding site for gating modifier toxins like Hanatoxin and a helical secondary structural arrangement was suggested. Due to the lack of complete structure in high resolution for such