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Molecular self-diffusion of intracellular metabolites in rat brain in vivo Investigated by Localized Proton NMR Diffusion Spectroscopy

✍ Scribed by Klaus-Dietmar Merboldt; Dirk Hörstermann; Wolfgang Hänicke; Harald Bruhn; Jens Frahm

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 418 KB
Volume: 29
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910290123

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✦ Synopsis

Abstract

Molecular self‐diffusion coefficients of water (0.75 ± 0.05), Nacetylaspartate (0.27 ± 0.04), creatines (0.27 ± 0.04), and cholines (0.28 ± 0.08) × 10^−5^ cm^2^ s^−1^ were obtained from localized proton NMR spectra of rat brain in vivo using diffusion‐weighted stimulated‐echo (STEAM) sequences with a diffusion time of (Δ − δ/3) = 17 ms.

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