Identification of a missense mutation an
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Mikesell, M. J.; Sobell, J. L.; Sommer, S. S.; McMurray, C. T.
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Article
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1996
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John Wiley and Sons
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English
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Schizophrenia is a complex and severe disorder of unknown cause and pathophysiology. In this study, we examined the opioid hypothesis for schizophrenia at the molecular level, focusing on the dopamineregulated proenkephalin A gene (chromosome 8q11.23-ql2). W e have screened 150 schizophrenic patient