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Molecular regulation of CD40 gene expression in macrophages and microglia

✍ Scribed by Etty N. Benveniste; Vince T. Nguyen; Duane R. Wesemann


Book ID
116275466
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
176 KB
Volume
18
Category
Article
ISSN
0889-1591

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Microglia are one of the major glial cell types within the central nervous system, and can function as immune effector cells upon activation. CD40 is a cell surface receptor belonging to the TNF receptor family that plays a critical role in the regulation of immune responses. In this study, we inves