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Molecular Recognition in Complexes of Telomeric DNA with TRF Proteins as Studied by Molecular Dynamics Simulations

✍ Scribed by Wieczor, Milosz; Tobiszewski, Adrian; Wityk, Pawel; Czub, Jacek


Book ID
122335330
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
38 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract The RNA recognition motif (RRM) is one of the most common RNA binding domains. We have investigated the contribution of three highly conserved aromatic amino acids to RNA binding by the N‐terminal RRM of the U1A protein. Recently, we synthesized a modified base (A‐4CPh) in which a pheny