Whenever hydrogen bonding is involved in molecular recognition, the possibility of a proton transfer from the donor to the acceptor arises. In most cases the pK a of the donor is far enough above the pK a of the conjugate acid of the acceptor for it to be clear that no proton transfer will occur. Ho
โฆ LIBER โฆ
Molecular recognition: A thermodynamic study of non bonded interactions in aqueous solutions of iminoacids. Effects of steric and geometric isomerism
โ Scribed by Giuseppina Castronuovo; Vittorio Elia; Filomena Velleca
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 523 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0095-9782
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The cis/trans conformational equilibrium of the two Ac-Pro isomers of the beta-turn model dipeptide [13C]-Ac-L-Pro-D-Ala-NHMe, 98% 13C enriched at the acetyl carbonyl atom, was investigated by the use of variable temperature gradient enhanced 1H-nmr, two-dimensional (2D) 1H,1H nuclear Overhauser eff