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Molecular properties of P2X receptors

✍ Scribed by Jonathan A. Roberts; Catherine Vial; Helen R. Digby; Kelvin C. Agboh; Hairuo Wen; Amelia Atterbury-Thomas; Richard J. Evans

Publisher: Springer
Year: 2006
Tongue: English
Weight: 361 KB
Volume: 452
Category: Article
ISSN: 0031-6768
DOI: 10.1007/s00424-006-0073-6

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## Abstract Among seven members of P2X ionotropic receptors activated by extracellular ATP, the P2X~7~ subtype is unique in that it can function as a cation channel, a nonselective pore, or even a signaling complex coupled with multiple downstream components. Several roles of P2X~7~ receptors have