Prognosis of DLCL patients is variable and associated with well-deยฎned risk factors. In the past decade several pretreatment variables have been incorporated into prognostic models to predict the death risk of individual patients. The International Prognostic Index (IPI), developed in an internation
Molecular prognostic factors in diffuse large B-cell lymphoma
โ Scribed by Daniel Morgensztern; Izidore S. Lossos
- Book ID
- 107531913
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 375 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1527-2729
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๐ SIMILAR VOLUMES
## Abstract Diffuse large Bโcell lymphoma (DLBCL) is a biologically heterogeneous disease for which the current approach to treatment is only successful for 50% of patients. The prognostic value of various clinical and biological factors in predicting treatment outcome is discussed in this paper. A
B-lineage diffuse large cell lymphoma (B-DLCL) arising de novo is chatacterized by a marked degree of clinical heterogeneity. To determine whether or not the clinical heterogeneity of de novo B-DLCL is reflected by heterogeneity in the molecular features of these tumors, we investigated the pattern