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Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas

✍ Scribed by Bonner, Allison E; Lemon, William J; Devereux, Theodora R; Lubet, Ronald A; You, Ming


Book ID
110068315
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
366 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract Mice bearing LP07 lung adenocarcinoma show some characteristics that are similar to those present in patients with NSCLC. LP07 tumor‐bearing mice develop the paraneoplastic syndromes of cachexia, leukocytosis and hypercalcemia. These symptoms may be partly due to a systemic inflammatory