Engraftment of chronic myeloid leukemia
โ
Christine F. Hoyle; Robert S. Negrin
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 290 KB
๐ 2 views
Chronic myeloid leukemia (CML) is a clonal disorder of primitive hematopoietic stem cells characterized by a reciprocal translocation between chromosomes 9 and 22. Animal models of CML would be useful to study the biology and potential therapies in this disease. Mice with severe combined immunodefic