Molecular Profiling of Anemia in Acute Renal Allograft Rejection Using DNA Microarrays
β Scribed by Mei-Sze Chua; Christopher Barry; Xin Chen; Oscar Salvatierra; Minnie M. Sarwal
- Book ID
- 114423658
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 215 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1600-6135
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Acute cellular rejection (ACR) is still a major problem in organ transplantation, and its genetic and molecular mechanisms remain poorly understood. We used DNA microarrays to investigate the gene expression profiles in ACR. We hypothesized that changes of gene expression in grafts could also be det
## Abstract Several recent reports have documented the value of intensive plasmapheresis as an adjunct to standard immunosuppressive therapy for patients suffering acute renal allograft rejection. We have treated four rejection episodes in three patients with intensive plasmapheresis and two reject