𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular processes and structural alterations in laser reshaping of cartilage

✍ Scribed by N. Ignatieva; O. Zakharkina; G. Leroy; E. Sobol; N. Vorobieva; S. Mordon

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
750 KB
Volume
4
Category
Article
ISSN
1612-2011

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✦ Synopsis

The effects of non-destructive laser irradiation on the structure and molecular processes in cartilage were studied using Raman microscopy, differential scanning calorimetry and biochemical analysis. A structural reorganization of the irradiated tissue similar to poliginization in polycrystalline solids was observed for the first time in a cartilage matrix. The difference in the Raman spectra of the irradiated and control samples was interpreted in term of a conformational alteration of glycosaminoglycan macromolecules in the reshaping mode. Laser induced modification of collagen macromolecules was not revealed by Raman spectroscopy. Thermal and biochemical analysis confirmed a preservation of triple helix for laser settings used for laser-induced stress relaxation and reshaping of cartilage.

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