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Molecular Pathways: Targeting MYC-induced Metabolic Reprogramming and Oncogenic Stress in Cancer

✍ Scribed by Li, B.; Simon, M. C.


Book ID
121341327
Publisher
American Association for Cancer Research
Year
2013
Tongue
English
Weight
387 KB
Volume
19
Category
Article
ISSN
1078-0432

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__