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Molecular pathways in DNA-DNA hybridization of surface-bound oligonucleotides

✍ Scribed by Hoefert, Moritz Julian ;Sambriski, Edward John ;José de Pablo, Juan

Book ID
125531324
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
517 KB
Volume
7
Category
Article
ISSN
1744-683X

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## Background The high binding specificity of short 10 to 30 mer oligonucleotide probes enables single base mismatch (MM) discrimination and thus provides the basis for genotyping and resequencing microarray applications. Recent experiments indicate that the underlying principles governing DNA micr